Article
Notch4 overexpression in ameloblastoma correlates with the solid/multicystic phenotype.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics - 1 Aug 2010
Siar Chong Huat, Nagatsuka Hitoshi, Chuah Kee Seng, Rivera Rosario Santos, Nakano Keisuke, Ng Kok Han, Kawakami Toshiyuki
Abstract excerpt
OBJECTIVE: Notch signaling has been implicated in cell fate decisions during odontogenesis and tumorigenesis of some odontogenic neoplasms; however, its role in solid/multicystic (SA), unicystic (UA), and recurrent (RA) ameloblastoma remains unclear. The aim of this study was to determine Notch receptor and ligand expressions in these subtypes and to speculate on their significance. METHODS: Notch receptors...
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