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Programmed death-ligand 1 regulates ameloblastoma growth and recurrence

16 Apr 2025

Abstract excerpt

Abstract Tumor cell-intrinsic programmed death-ligand 1 (PD-L1) signals mediate tumor initiation, progression and metastasis, but their effects in ameloblastoma (AM) have not been reported. In this comprehensive study, we observed marked upregulation of PD-L1 in AM tissues and revealed the robust correlation between elevated PD-L1 expression and increased tumor growth and recurrence rates. Notably, we found that...

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PMID: 40240323
DOI: 10.1038/s41368-025-00364-w

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