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Article

Retinoic acid enhances sensitivity of neuroblastoma cells for imatinib mesylate.

Pediatric blood & cancer - 1 Sept 2010

Neumann Ingo, Foell Jürgen L, Bremer Marianne, Volkmer Ines, Korholz Dieter, Burdach Stefan, Staege Martin S

Abstract excerpt

BACKGROUND: Retinoids can induce differentiation of neuroblastoma (NB) cells and are in clinical use for the treatment of patients with NB. Despite improvements of standard treatment during the last years, many patients with NB still relapse and new treatment options for these patients are required. PROCEDURE: We analyzed NB cells after incubation with retinoids by using Affymetrix HG_U133A microarrays, reverse...

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PMID: 20658618
DOI: 10.1002/pbc.22603

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KIT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Retinoic acid enhances sensitivity of neuroblastoma cells for imatinib mesylate.PMID 20658618Read ↗

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Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiationSemantic proximity Read ↗

Gene expression and neuroblastoma cell differentiation in response to retinoic acid: differential effects of 9-cis and all-trans retinoic acid.Semantic proximity Read ↗

Increasing the intracellular availability of all-trans retinoic acid in neuroblastoma cellsSemantic proximity Read ↗

MicroRNA Mediates DNA Demethylation Events Triggered by Retinoic Acid during Neuroblastoma Cell DifferentiationSemantic proximity Read ↗

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Metabolic characteristics of 13‐cis‐retinoic acid (isotretinoin) and anti‐tumour activity of the 13‐cis‐retinoic acid metabolite 4‐oxo‐13‐cis‐retinoic acid in neuroblastomaSemantic proximity Read ↗

Why Differentiation Therapy Sometimes Fails: Molecular Mechanisms of Resistance to RetinoidsSemantic proximity Read ↗

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