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Article

Functional roles of the conserved Glu304 loop of Bacillus subtilis glutamine synthetase.

Journal of bacteriology - 1 Oct 2010

Wray Lewis V, Fisher Susan H

Abstract excerpt

The enzymatic activity of Bacillus subtilis glutamine synthetase (GS), which catalyzes the synthesis of glutamine from ammonium and glutamate, is regulated by glutamine feedback inhibition. The feedback-inhibited form of B. subtilis GS regulates the DNA-binding activities of the TnrA and GlnR nitrogen transcriptional factors. Bacterial GS proteins contain a flexible seven-residue loop, the Glu304 flap, that...

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Identifiers

PMID: 20656908
DOI: 10.1128/JB.00509-10
PMCID: PMC2944536

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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