Article
Day 15 bone marrow driven double induction in young adult patients with acute myeloid leukemia: feasibility, toxicity, and therapeutic results.
American journal of hematology - 1 Sept 2010
Ferrara Felicetto, Izzo Tiziana, Criscuolo Clelia, Riccardi Cira, Celentano Maria, Mele Giuseppina
Abstract excerpt
The strategy named double induction (DI) in acute myeloid leukemia (AML) consists of two courses of chemotherapy irrespective of the degree of cytoreduction in the bone marrow (BM) after the first course, unless severe complications prohibit its application. We describe treatment results from a series of 33 patients in whom DI was adopted only after demonstration of persistence of more than 10% blast cells at day...
Topics
- Adolescent
- Adult
- Antineoplastic Combined Chemotherapy Protocols
- Blast Crisis
- Bone Marrow
- Chromosome Aberrations
- Cytarabine
- Disease-Free Survival
- Etoposide
- Female