Article
Correlation between polymorphisms of the reduced folate carrier gene (SLC19A1) and survival after pemetrexed-based therapy in non-small cell lung cancer: a North Central Cancer Treatment Group-based exploratory study.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Sept 2010
Adjei Araba A, Salavaggione Oreste E, Mandrekar Sumithra J, Dy Grace K, Ziegler Katie L Allen, Endo Chiaki, Molina Julian R, Schild Steven E, Adjei Alex A
Abstract excerpt
PURPOSE: To correlate polymorphisms in genes involved in the transport, activation, and inactivation of pemetrexed with the outcome of patients with advanced non-small cell lung cancer (NSCLC) treated with pemetrexed. EXPERIMENTAL DESIGN: Data from a phase II NSCLC trial evaluating the optimal sc...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.