Article
The Drosophila SUN protein Spag4 cooperates with the coiled-coil protein Yuri Gagarin to maintain association of the basal body and spermatid nucleus.
Journal of cell science - 15 Aug 2010
Kracklauer Martin P, Wiora Heather M, Deery William J, Chen Xin, Bolival Benjamin, Romanowicz Dwight, Simonette Rebecca A, Fuller Margaret T, Fischer Janice A, Beckingham Kathleen M
Abstract excerpt
Maintaining the proximity of centrosomes to nuclei is important in several cellular contexts, and LINC complexes formed by SUN and KASH proteins are crucial in this process. Here, we characterize the presumed Drosophila ortholog of the mammalian SUN protein, sperm-associated antigen 4 (Spag4, previously named Giacomo), and demonstrate that Spag4 is required for centriole and nuclear attachment during...
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