Article
Length control of the injectisome needle requires only one molecule of Yop secretion protein P (YscP).
Proceedings of the National Academy of Sciences of the United States of America - 3 Aug 2010
Wagner Stefanie, Stenta Marco, Metzger Lisa C, Dal Peraro Matteo, Cornelis Guy R
Abstract excerpt
The needle length of the Yersinia spp. injectisome is determined by Yop secretion protein P (YscP), an early substrate of the injectisome itself. There is a linear correlation between the length of YscP and the length of the needle, suggesting that YscP acts as a molecular ruler. However, it is not known whether one single molecule of YscP suffices to control the length of one needle or whether several molecules...
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