Article
Rationale for cross-species infection and cross-subtype mutation in hemagglutinins from influenza A virus.
Interdisciplinary sciences, computational life sciences - 1 Dec 2009
Yan Shao-Min, Wu Guang
Abstract excerpt
The current H1N1 swine pandemic raises the question why the cross-species infection and cross-subtype mutation are so easy. In this study, we use ANOVA to analyze all influenza A virus hemagglutinins available in database in order to answer this question. The results show that there are differences between species and between subtypes in most cases, but the intra-subtype/species variation is generally larger than...
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