Roles of minor pilin subunits Spy0125 and Spy0130 in the serotype M1 Streptococcus pyogenes strain SF370.

doi:10.1128/JB.00071-10

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Article

Roles of minor pilin subunits Spy0125 and Spy0130 in the serotype M1 Streptococcus pyogenes strain SF370.

Journal of bacteriology - 1 Sept 2010

Smith Wendy D, Pointon Jonathan A, Abbot Emily, Kang Hae Joo, Baker Edward N, Hirst Barry H, Wilson Janet A, Banfield Mark J, Kehoe Michael A

Abstract excerpt

Adhesive pili on the surface of the serotype M1 Streptococcus pyogenes strain SF370 are composed of a major backbone subunit (Spy0128) and two minor subunits (Spy0125 and Spy0130), joined covalently by a pilin polymerase (Spy0129). Previous studies using recombinant proteins showed that both minor subunits bind to human pharyngeal (Detroit) cells (A. G. Manetti et al., Mol. Microbiol. 64:968-983, 2007),...

Topics

Bacterial Adhesion
Bacterial Proteins
Cell Line, Tumor
Chromatography, Liquid
Fimbriae Proteins
Humans
Mutation
Polymerase Chain Reaction
Streptococcus pyogenes
Tandem Mass Spectrometry

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Identifiers

PMID: 20639332
DOI: 10.1128/JB.00071-10
PMCID: PMC2937429

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