Article
No evidence for shorter leukocyte telomere length in Parkinson's disease patients.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Nov 2010
Eerola Johanna, Kananen Laura, Manninen Kaisa, Hellström Olli, Tienari Pentti J, Hovatta Iiris
Abstract excerpt
Telomeres constitute the protective ends of chromosomes. They become shorter after each cell division, and therefore, telomere length is considered as an indicator of cellular aging. Interestingly, both inflammation and oxidative stress, which play a role in the etiology of Parkinson's disease (PD), may accelerate telomere shortening. Furthermore, it has been suggested that leukocyte telomere shortening may be...
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