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Article

Accelerated telomere shortening independent of LRRK2 variants in Chinese patients with Parkinson's disease.

Aging - 29 Oct 2020

Wu Yue, Pei Yuqing, Yang Zhuo, Li Kexin, Lou Xiaoying, Cui Wei

Abstract excerpt

Oxidative stress and inflammation play vital roles in Parkinson's disease (PD) development. Thus, telomere length is expected to be shortened in this disease, but current data are inconclusive. We performed a case-control study of 261 patients with PD and 270 sex and age-matched healthy controls treated at the Peking Union Medical College Hospital. We found leucocyte telomere length (LTL) was significantly...

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Identifiers

PMID: 33122450
DOI: 10.18632/aging.103878
PMCID: PMC7655166

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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