Article
Reduced electromotility of outer hair cells associated with connexin-related forms of deafness: an in silico study of a cochlear network mechanism.
Journal of the Association for Research in Otolaryngology : JARO - 1 Dec 2010
Mistrík Pavel, Ashmore Jonathan F
Abstract excerpt
Mutations in the GJB2 gene encoding for the connexin 26 (Cx26) protein are the most common source of nonsyndromic forms of deafness. Cx26 is a building block of gap junctions (GJs) which establish electrical connectivity in distinct cochlear compartments by allowing intercellular ionic (and metab...
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