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Article

Association between a high-risk autism locus on 5p14 and social communication spectrum phenotypes in the general population.

The American journal of psychiatry - 1 Nov 2010

St Pourcain Beate, Wang Kai, Glessner Joseph T, Golding Jean, Steer Colin, Ring Susan M, Skuse David H, Grant Struan F A, Hakonarson Hakon, Smith George D, Davey Smith George

Abstract excerpt

OBJECTIVE: Recent genome-wide analysis identified a genetic variant on 5p14.1 (rs4307059), which is associated with risk for autism spectrum disorder. This study investigated whether rs4307059 also operates as a quantitative trait locus underlying a broader autism phenotype in the general population, focusing specifically on the social communication aspect of the spectrum. METHOD: Study participants were 7,313...

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Identifiers

PMID: 20634369
DOI: 10.1176/appi.ajp.2010.09121789
PMCID: PMC3008767

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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