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Article

Prognostic significance of XIAP expression in DLBCL and effect of its inhibition on AKT signalling

17 Jun 2010

Abstract excerpt

The inhibitor of apoptosis protein (IAP) family member X-linked inhibitor of apoptosis protein (XIAP) is essential for cell survival in lymphoma. However, the role of XIAP overexpression in diffuse large B-cell lymphoma (DLBCL) is not fully elucidated. Therefore, we analysed the expression of XIAP protein and its clinicopathological correlation in a large cohort of DLBCLs by immunohistochemistry in a tissue...

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PMID: 20632385
DOI: 10.1002/path.2747

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