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Article

Characterization of a Putative Ancestor of Coxsackievirus B5

15 Jul 2010

Abstract excerpt

Like other RNA viruses, coxsackievirus B5 (CVB5) exists as circulating heterogeneous populations of genetic variants. In this study, we present the reconstruction and characterization of a probable ancestral virion of CVB5. Phylogenetic analyses based on capsid protein-encoding regions (the VP1 gene of 41 clinical isolates and the entire P1 region of eight clinical isolates) of CVB5 revealed two major...

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PMID: 20631132
DOI: 10.1128/jvi.00071-10

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