Article
Comparative genome analysis of a large Dutch Legionella pneumophila strain collection identifies five markers highly correlated with clinical strains.
BMC genomics - 15 Jul 2010
Yzerman Ed, den Boer Jeroen W, Caspers Martien, Almal Arpit, Worzel Bill, van der Meer Walter, Montijn Roy, Schuren Frank
Abstract excerpt
BACKGROUND: Discrimination between clinical and environmental strains within many bacterial species is currently underexplored. Genomic analyses have clearly shown the enormous variability in genome composition between different strains of a bacterial species. In this study we have used Legionella pneumophila, the causative agent of Legionnaire's disease, to search for genomic markers related to pathogenicity....
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