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Article

[Effects of simvastatin on proliferation and transition of phenotype in PDGF-BB-induced pulmonary artery smooth muscle cells].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition - 1 May 2010

Wang Xiao-Qin, Zhou Tong-Fu, Liu Han-Min, Wang Juan, Wang Xian-Min, Liu Bin

Abstract excerpt

OBJECTIVE: To investigate the effects of simvastatin on inhibiting cell phenotype and potential mechanism in PASMC induced by PDGF-BB. METHODS: PASMC isolated from SD rats and cultured in vitro were induced by PDGF-BB and then intervened by simvastatin and Y-27632. Flow cytometry were performed t...

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Source

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PMID: 20629317

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20629317-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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