Article
N-terminal Pro brain natriuretic peptide is a reliable biomarker of reduced myocardial contractility in patients with lamin A/C gene mutations.
International journal of cardiology - 1 Sept 2011
Meune Christophe, Wahbi Karim, Gobeaux Camille, Duboc Denis, Pecker Françoise, Bonne Gisèle
Abstract excerpt
BACKGROUND: Recently, concerns have been raised about a possible lack of sensitivity of biomarkers to detect left ventricular (LV) dysfunction in patients with myopathies. We examined the ability of the N-terminal brain natriuretic peptide (NT-proBNP) to detect LV or right ventricular (RV) dysfunction in patients with lamin A/C (LMNA) gene mutations. METHODS: We prospectively measured plasma NT-proBNP in...
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