Article
Mid-myocardial fibrosis by cardiac magnetic resonance in patients with lamin A/C cardiomyopathy: possible substrate for diastolic dysfunction.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance - 1 Jan 2007
Raman Subha V, Sparks Elizabeth A, Baker Peter M, McCarthy Beth, Wooley Charles F
Abstract excerpt
AIMS: We sought to identify patterns of myocardial fibrosis in vivo in patients with lamin cardiomyopathy, and to determine its functional significance. METHODS AND RESULTS: Eleven patients sharing the identical mutation in LMNA without contraindication to magnetic resonance were identified from a 1016-member pedigree. Eight autopsy hearts from deceased relatives were reviewed. Patients and age-matched controls...
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