Article
Impact of age and sex on mycobacterial immunity in an area of high tuberculosis incidence.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Aug 2010
Gallant C J, Cobat A, Simkin L, Black G F, Stanley K, Hughes J, Doherty T M, Hanekom W A, Eley B, Beyers N, Jaïs J-P, van Helden P, Abel L, Alcaïs A, Hoal E G, Schurr E
Abstract excerpt
SETTING: The extent of immune reactivity measured by the tuberculin skin test (TST) and interferon-gamma (IFN-gamma) T-cell assays is usually not analysed. OBJECTIVE: To determine the impact of age and sex on assay positivity and on the extent of reactivity of both TST and T-cell assays in young persons in an area of South Africa with high TB transmission. RESULTS: Age had a strong impact on assay positivity for...
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