Article
Quantitative association tests of immune responses to antigens of Mycobacterium tuberculosis: a study of twins in West Africa.
Twin research : the official journal of the International Society for Twin Studies - 1 Dec 2004
Wiart Amanda, Jepson Annette, Banya Winston, Bennett Steve, Whittle Hilton, Martin Nicholas G, Hill Adrian V S
Abstract excerpt
There is now considerable evidence that host genetic factors are important in determining the outcome of infection with Mycobacterium tuberculosis (MTB). The aim of this study was to assess the role of several candidate genes in the variation observed in the immune responses to MTB antigens. In-vitro assays of T-cell proliferation, an in-vivo intradermal delayed hypersensitivity response; cytokine and antibody...
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