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Article

Lysine 419 targets human glucocorticoid receptor for proteasomal degradation.

Steroids - 1 Dec 2010

Wallace Andrew D, Cao Yan, Chandramouleeswaran Sindhu, Cidlowski John A

Abstract excerpt

Glucocorticoid receptors (GRs) are members of a highly conserved family of ligand dependent transcription factors which following hormone binding undergo homologous down-regulation reducing the levels of receptor protein. This decline in human GR (hGR) is due in part to a decrease in protein rece...

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Identifiers

PMID: 20619282
DOI: 10.1016/j.steroids.2010.06.015
PMCID: PMC2926287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20619282-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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