Article
Heterogeneity in phenotype and function of CD8+ and CD4/CD8 double-negative Natural Killer T cell subsets in sooty mangabeys.
Journal of medical primatology - 1 Aug 2010
Rout Namita, Else James G, Yue Simon, Connole Michelle, Exley Mark A, Kaur Amitinder
Abstract excerpt
BACKGROUND: We have recently reported the presence of CD8(+) and CD4/8 double-negative (DN) natural killer T (NKT) lymphocytes in sooty mangabeys. To investigate differences in the two NKT cell subsets, we compared the phenotype and function of sooty mangabey CD8(+) and DN NKT cells. METHODS: Flow-sorted NKT lymphocytes from one SIV-negative sooty mangabey were subjected to limiting dilution cloning. Invariant...
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