Article
Cloning of nocardioform DNA conferring the ability to inactivate rifampicin.
FEMS microbiology letters - 15 Apr 1991
Andersen S J, Dabbs E R
Abstract excerpt
A novel mechanism of resistance to rifampicin has recently been reported in which this antibiotic is inactivated. Here we describe the cloning of DNA from a nocardiofrom strain conferring this ability to inactivate rifampicin. Cloning was on the basis of complementation, as an increased resistance to the antibiotic. The genetic information was on a 8.3-kb BglII fragment.
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