Article
Novel single nucleotide polymorphisms of the caprine PC1 gene and association with growth traits.
Biochemical genetics - 1 Oct 2010
Sun Jiajie, Zhang Chunlei, Fang Xingtang, Lei Chuzhao, Lan Xianyong, Chen Hong
Abstract excerpt
Proprotein convertase 1 (PC1) is an endopeptidase involved in proteolytic processing of peptide hormone precursors in granules of the regulated secretory pathway in endocrine cells. Mutations in the PC1 gene are thought to cause obesity, and multiple alternatively spliced transcript variants have been described for this gene. In this study, based on PCR-SSCP and DNA sequencing methods, polymorphisms of the PC1...
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