Article
Polymorphisms in an obesity-related gene (PCSK1) are associated with fat deposition and production traits in Italian heavy pigs.
Animal : an international journal of animal bioscience - 1 Dec 2012
Fontanesi L, Bertolini F, Scotti E, Trevisi P, Buttazzoni L, Dall'olio S, Davoli R, Bosi P, Russo V
Abstract excerpt
The proprotein convertase subtilisin/kexin type 1 (PCSK1) gene encodes the prohormone convertase 1/3 enzyme that processes prohormones into functional hormones that, in turn, regulate central and peripheral energy metabolism. Mutations in the human PCSK1 gene cause severe monogenic obesity or confer risk of obesity. We herein investigated the porcine PCSK1 gene with the aim of identifying polymorphisms associated...
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