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Article

Mutant TAR DNA-binding protein-43 induces oxidative injury in motor neuron-like cell.

Neuroscience - 15 Sept 2010

Duan W, Li X, Shi J, Guo Y, Li Z, Li C

Abstract excerpt

Various missense mutations were identified in TAR DNA-binding protein-43 (TDP-43) in patients with amyotrophic lateral sclerosis (ALS). To explore the toxic effect of mutant TDP-43, we generated stable transfection of wild-type and mutant TDP-43 in motor neuron-like cell line. We found that mutan...

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Source

Identifiers

PMID: 20600671
DOI: 10.1016/j.neuroscience.2010.06.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20600671-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Mutant TAR DNA-binding protein-43 induces oxidative injury in motor neuron-like cell.PMID 20600671Read ↗

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