Article
Differential effects of chromosome 9p21 variation on subphenotypes of intracranial aneurysm: site distribution.
Stroke - 1 Aug 2010
Nakaoka Hirofumi, Takahashi Tomoko, Akiyama Koichi, Cui Tailin, Tajima Atsushi, Krischek Boris, Kasuya Hidetoshi, Hata Akira, Inoue Ituro
Abstract excerpt
BACKGROUND AND PURPOSE: Recently, a genome-wide association study identified associations between single nucleotide polymorphisms on chromosome 9p21 and risk of harboring intracranial aneurysm (IA). Aneurysm characteristics or subphenotypes of IAs, such as history of subarachnoid hemorrhage, presence of multiple IAs and location of IAs, are clinically important. We investigated whether the association between...
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