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Article

Identification and characterization of retinoblastoma gene mutations disturbing apoptosis in human breast cancers.

Molecular cancer - 1 Jul 2010

Berge Elisabet Ognedal, Knappskog Stian, Geisler Stephanie, Staalesen Vidar, Pacal Marec, Børresen-Dale Anne-Lise, Puntervoll Pål, Lillehaug Johan Richard, Lønning Per Eystein

Abstract excerpt

BACKGROUND: The tumor suppressor pRb plays a key role regulating cell cycle arrest, and disturbances in the RB1 gene have been reported in different cancer forms. However, the literature reports contradictory findings with respect to a pro--versus anti--apoptotic role of pRb, and the consequence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20594292
DOI: 10.1186/1476-4598-9-173
PMCID: PMC2908580

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20594292-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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