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Article

Education, tobacco smoking, alcohol consumption, and IL-2 and IL-6 gene polymorphisms in the survival of head and neck cancer.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Oct 2011

López R V M, Zago M A, Eluf-Neto J, Curado M P, Daudt A W, da Silva-Junior W A, Zanette D L, Levi J E, de Carvalho M B, Kowalski L P, Abrahão M, de Góis-Filho J F, Boffetta P, Wünsch-Filho V

Abstract excerpt

The association of education, tobacco smoking, alcohol consumption, and interleukin-2 (IL-2 +114 and -384) and -6 (IL-6 -174) DNA polymorphisms with head and neck squamous cell carcinoma (HNSCC) was investigated in a cohort study of 445 subjects. IL-2 and IL-6 genotypes were determined by real-time PCR. Cox regression was used to estimate hazard ratios (HR) and 95% confidence intervals (95%CI) of disease-specific...

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Identifiers

PMID: 21845339
DOI: 10.1590/s0100-879x2011007500097

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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