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Article

Association of aldehyde dehydrogenase 2 gene polymorphism with pancreatic cancer but not colon cancer.

Geriatrics & gerontology international - 1 Jul 2010

Miyasaka Kyoko, Hosoya Hiroko, Tanaka Yasuo, Uegaki Satoko, Kino Kenji, Shimokata Hiroshi, Kawanami Takako, Funakoshi Akihiro

Abstract excerpt

AIMS: Most of the acetaldehyde, a recognized animal carcinogen, generated during alcohol metabolism is eliminated by liver mitochondrial aldehyde dehydrogenase 2 (ALDH2). More than 40% of Japanese people have the inactive form of ALDH2, and inactive ALDH2 is a risk factor for multiple cancer of the esophagus, as well as head and neck cancer. Possible associations between pancreatic cancer and ALDH2 gene...

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Source

Identifiers

PMID: 20590827
DOI: 10.1111/j.1447-0594.2010.00616.x

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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