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Three‐dimensional culture systems for the expansion of pluripotent embryonic stem cells

29 Jun 2010

Abstract excerpt

Mouse embryonic stem cell (ESC) lines, and more recently human ESC lines, have become valuable tools for studying early mammalian development. Increasing interest in ESCs and their differentiated progeny in drug discovery and as potential therapeutic agents has highlighted the fact that current two-dimensional (2D) static culturing techniques are inadequate for large-scale production. The culture of mammalian...

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PMID: 20589846
DOI: 10.1002/bit.22850

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