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Article

Elevated expression of TMEM205, a hypothetical membrane protein, is associated with cisplatin resistance

29 Jun 2010

Abstract excerpt

Development of cisplatin resistance in cancer cells appears to be a consequence of multiple epigenetic alterations in genes involved in DNA damage repair, proto-oncogenes, apoptosis, transporters, transcription factors, etc. In this study, we found that expression of the hypothetical transmembrane protein TMEM205 (previously known as MBC3205) is associated with cisplatin resistance. TMEM205 was first detected by...

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PMID: 20589834
DOI: 10.1002/jcp.22287

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