Article
Establishment and characterization of a murine xenograft model of appendiceal mucinous adenocarcinoma.
International journal of experimental pathology - 1 Aug 2010
Mavanur Arun A, Parimi Vamsi, O'Malley Mark, Nikiforova Marina, Bartlett David L, Davison Jon M
Abstract excerpt
We describe the clinical, pathologic and molecular characteristics of a xenograft model of metastatic mucinous appendiceal adenocarcinoma. Tumours from patients with mucinous appendiceal neoplasms were implanted in nude mice and observed for evidence of intraperitoneal tumour growth. Morphologic and immunohistochemical features, temporal growth characteristics relative to controls, and loss of heterozygosity...
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