Article
NleG Type 3 effectors from enterohaemorrhagic Escherichia coli are U-Box E3 ubiquitin ligases.
PLoS pathogens - 24 Jun 2010
Wu Bin, Skarina Tatiana, Yee Adelinda, Jobin Marie-Claude, Dileo Rosa, Semesi Anthony, Fares Christophe, Lemak Alexander, Coombes Brian K, Arrowsmith Cheryl H, Singer Alexander U, Savchenko Alexei
Abstract excerpt
NleG homologues constitute the largest family of Type 3 effectors delivered by pathogenic E. coli, with fourteen members in the enterohaemorrhagic (EHEC) O157:H7 strain alone. Identified recently as part of the non-LEE-encoded (Nle) effector set, this family remained uncharacterised and shared no sequence homology to other proteins including those of known function. The C-terminal domain of NleG2-3 (residues 90...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.