Article
Redistribution of mitochondria leads to bursts of ATP production during spontaneous mouse oocyte maturation.
Journal of cellular physiology - 1 Sept 2010
Yu Yuansong, Dumollard Remi, Rossbach Andreas, Lai F Anthony, Swann Karl
Abstract excerpt
During mammalian oocyte maturation there are marked changes in the distribution of mitochondria that supply the majority of the cellular ATP. Such redistribution of mitochondria is critical for oocyte quality, as oocytes with a poor developmental potential display aberrant mitochondrial distribution and lower ATP levels. Here we have investigated the dynamics of mitochondrial ATP production throughout spontaneous...
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