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Mitochondrial signaling and fertilization

23 Sept 2007

Abstract excerpt

The magnitude of the potential difference (polarity) across the inner mitochondrial membrane (DeltaPsim) determines levels of several mitochondrial activities, including ATP generation, focal regulate calcium homeostasis and organelle volume homeostasis. We investigated whether a domain of mitochondria in the mouse oocyte, characterized by high DeltaPsim and a unique location in the subplasmalemmal cytoplasm, is...

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PMID: 17893093
DOI: 10.1093/molehr/gam068

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