Article
Allele-specific expression of the MAOA gene and X chromosome inactivation in in vitro produced bovine embryos.
Molecular reproduction and development - 1 Jul 2010
Ferreira A R, Machado G M, Diesel T O, Carvalho J O, Rumpf R, Melo E O, Dode M A N, Franco M M
Abstract excerpt
During embryogenesis, one of the two X chromosomes is inactivated in embryos. The production of embryos in vitro may affect epigenetic mechanisms that could alter the expression of genes related to embryo development and X chromosome inactivation (XCI). The aim of this study was to understand XCI during in vitro, pre-implantation bovine embryo development by characterizing the allele-specific expression pattern...
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