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Article

Interobserver variability in the evaluation of mismatch repair protein immunostaining.

Human pathology - 1 Oct 2010

Klarskov Louise, Ladelund Steen, Holck Susanne, Roenlund Karina, Lindebjerg Jan, Elebro Jacob, Halvarsson Britta, von Salomé Jenny, Bernstein Inge, Nilbert Mef

Abstract excerpt

Immunohistochemical staining for mismatch repair proteins has during recent years been established as a routine analysis in many pathology laboratories with the aim to identify tumors linked to the hereditary nonpolyposis colorectal cancer syndrome. Despite widespread application, data on reliability are lacking. We therefore evaluated interobserver variability among 6 pathologists, 3 experienced gastrointestinal...

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Share to Adenosine Triphosphatases
Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mismatch Repair

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Share to Mismatch Repair Endonuclease PMS2

Share to MutL Protein Homolog 1

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Source

Identifiers

PMID: 20573374
DOI: 10.1016/j.humpath.2010.03.003

Genes

MLH1
MSH2
MSH6
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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