Article
SDHB/SDHA immunohistochemistry in pheochromocytomas and paragangliomas: a multicenter interobserver variation analysis using virtual microscopy: a Multinational Study of the European Network for the Study of Adrenal Tumors (ENS@T).
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jun 2015
Papathomas Thomas G, Oudijk Lindsey, Persu Alexandre, Gill Anthony J, van Nederveen Francien, Tischler Arthur S, Tissier Frédérique, Volante Marco, Matias-Guiu Xavier, Smid Marcel, Favier Judith, Rapizzi Elena, Libe Rosella, Currás-Freixes Maria, Aydin Selda, Huynh Thanh, Lichtenauer Urs, van Berkel Anouk, Canu Letizia, Domingues Rita, Clifton-Bligh Roderick J, Bialas Magdalena, Vikkula Miikka, Baretton Gustavo, Papotti Mauro, Nesi Gabriella, Badoual Cécile, Pacak Karel, Eisenhofer Graeme, Timmers Henri J, Beuschlein Felix, Bertherat Jérôme, Mannelli Massimo, Robledo Mercedes, Gimenez-Roqueplo Anne-Paule, Dinjens Winand Nm, Korpershoek Esther, de Krijger Ronald R
Abstract excerpt
Despite the established role of SDHB/SDHA immunohistochemistry as a valuable tool to identify patients at risk for familial succinate dehydrogenase-related pheochromocytoma/paraganglioma syndromes, the reproducibility of the assessment methods has not as yet been determined. The aim of this study was to investigate interobserver variability among seven expert endocrine pathologists using a web-based virtual...
Read the complete abstract on PubMed