Article
The PRiMA-linked cholinesterase tetramers are assembled from homodimers: hybrid molecules composed of acetylcholinesterase and butyrylcholinesterase dimers are up-regulated during development of chicken brain.
The Journal of biological chemistry - 27 Aug 2010
Chen Vicky P, Xie Heidi Q, Chan Wallace K B, Leung K Wing, Chan Gallant K L, Choi Roy C Y, Bon Suzanne, Massoulié Jean, Tsim Karl W K
Abstract excerpt
Acetylcholinesterase (AChE) is anchored onto cell membranes by the transmembrane protein PRiMA (proline-rich membrane anchor) as a tetrameric globular form that is prominently expressed in vertebrate brain. In parallel, the PRiMA-linked tetrameric butyrylcholinesterase (BChE) is also found in the...
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