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Article

Epithelial-mesenchymal transition of epicardial mesothelium is a source of cardiac CD117-positive stem cells in adult human heart.

Journal of molecular and cellular cardiology - 1 Nov 2010

Di Meglio Franca, Castaldo Clotilde, Nurzynska Daria, Romano Veronica, Miraglia Rita, Bancone Ciro, Langella Giuseppina, Vosa Carlo, Montagnani Stefania

Abstract excerpt

Epithelial-mesenchymal transition is implicated in the remodelling of tissues during development and in the adult life. In the heart, it gives origin to progenitors of fibroblasts, coronary endothelium, smooth muscle cells, and cardiomyocytes. Moreover, epicardially-derived cells determine myocardial wall thickness and Purkinje fibre network. Recently, the presence of numerous cardiac stem cells in the...

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Identifiers

PMID: 20566360
DOI: 10.1016/j.yjmcc.2010.05.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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