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Article

Evidence for separation of HCV subtype 1a into two distinct clades.

Journal of viral hepatitis - 1 Sept 2011

Pickett B E, Striker R, Lefkowitz E J

Abstract excerpt

The nucleotide sequence diversity present among hepatitis C virus (HCV) isolates allows rapid adjustment to exterior forces including host immunity and drug therapy. This viral response reflects a combination of a high rate of replication together with an error-prone RNA-dependent RNA polymerase, providing for the selection and proliferation of the viruses with the highest fitness. We examined HCV subtype 1a...

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Identifiers

PMID: 20565573
DOI: 10.1111/j.1365-2893.2010.01342.x
PMCID: PMC2964416

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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