Article
KRAS, BRAF, EGFR and HER2 gene status in a Spanish population of colorectal cancer.
Molecular biology reports - 1 Feb 2011
Herreros-Villanueva Marta, Rodrigo Maximiliano, Claver Manuel, Muñiz Pilar, Lastra Enrique, García-Girón Carlos, Coma del Corral Maria Jesus
Abstract excerpt
To evaluate the KRAS, BRAF, EGFR, and HER2 gene status in colorectal cancer by novel techniques and evaluate whether anti-HER2 therapies could be offered in the treatment of these patients. There are conflicting data on the prevalence of BRAF mutations and EGFR and HER2 gene amplification in colorectal KRAS wild type patients. In our study we tried to evaluate these expressions and their relationship to future...
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