Article
Poorly differentiated carcinoma of the thyroid: validation of the Turin proposal and analysis of IMP3 expression.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2010
Asioli Sofia, Erickson Lori A, Righi Alberto, Jin Long, Volante Marco, Jenkins Sarah, Papotti Mauro, Bussolati Gianni, Lloyd Ricardo V
Abstract excerpt
The Turin Proposal algorithm defines poorly differentiated carcinoma on the basis of the presence of solid/trabecular/insular growth pattern, absence of conventional nuclear features of papillary carcinoma, and the presence of at least one of the following features: convoluted nuclei, mitotic activity > or =3/10 HPF, or tumor necrosis. IMP3 appears to have diagnostic and prognostic value in many solid tumors,...
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