Article
Reduction of abnormal behavioral response to brief restraint by information from other mice in dystrophin-deficient mdx mice.
Neuromuscular disorders : NMD - 1 Aug 2010
Yamamoto Kazuhiro, Yamada Daisuke, Kabuta Tomohiro, Takahashi Akio, Wada Keiji, Sekiguchi Masayuki
Abstract excerpt
We recently reported that dystrophin-deficient mdx mice exhibited a hypersensitive freezing response to fearful events such as brief restraint. In the present study, we ethologically characterized the restraint-induced freezing response in mdx mice. This response was evident when restrained mdx mice were released into a new cage or their home cage, but it was remarkably reduced in cages in which other individuals...
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