Article
Mice with vestibular deficiency display hyperactivity, disorientation, and signs of anxiety.
Behavioural brain research - 14 Sept 2009
Avni Reut, Elkan Tal, Dror Amiel A, Shefer Shachar, Eilam David, Avraham Karen B, Mintz Matti
Abstract excerpt
Previous studies revealed that vestibular cues are crucial for exploration in the absence of visual cues. The working hypothesis of this study was, accordingly, that mice with vestibular dysfunction would become disoriented or unable to globally explore an unfamiliar environment. In 2- and 3-month-old mutant headbanger (Hdb) mice, stereocilia of hair cells are abnormally elongated, yet maintain partial staircase...
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