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Article

Mutational analysis of TARDBP in neurodegenerative diseases.

Neurobiology of aging - 1 Nov 2011

Ticozzi Nicola, LeClerc Ashley Lyn, van Blitterswijk Marka, Keagle Pamela, McKenna-Yasek Diane M, Sapp Peter C, Silani Vincenzo, Wills Anne-Marie, Brown Robert H, Landers John E

Abstract excerpt

Neurodegenerative diseases are often characterized by the presence of aggregates of misfolded proteins. TDP-43 is a major component of these aggregates in amyotrophic lateral sclerosis (ALS), but has also been observed in Alzheimer's (AD) and Parkinson's Diseases (PD). In addition, mutations in t...

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Source

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Identifiers

PMID: 20031275
DOI: 10.1016/j.neurobiolaging.2009.11.018
PMCID: PMC2889148

Genes

TARDBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20031275-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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