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Article

Functional regulatory divergence of the innate immune system in interspecific Drosophila hybrids.

Molecular biology and evolution - 1 Nov 2010

Hill-Burns Erin M, Clark Andrew G

Abstract excerpt

In order to investigate divergence of immune regulation among Drosophila species, we have engaged in a study of innate immune function in F1 hybrids of Drosophila melanogaster and D. simulans. If pathways have diverged between the species such that incompatibilities have arisen between interacting components of the immune network, we expect the hybrids to display dysregulation of immune genes. We have quantified...

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Identifiers

PMID: 20551040
DOI: 10.1093/molbev/msq146
PMCID: PMC3107606

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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